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  1. Alzheimer's disease (AD) and age-related macular degeneration (AMD) share several pathological features including β-amyloid (Aβ) peptide accumulation, oxidative damage, and cell death. The causes of AD and AMD...

    Authors: Bhanu Dasari, Jaya RP Prasanthi, Gurdeep Marwarha, Brij B Singh and Othman Ghribi

    Citation: BMC Ophthalmology 2010 10:22

    Content type: Research article

    Published on:

  2. Prospective, observational studies that enroll large numbers of patients with few exclusion criteria may better reflect actual ongoing clinical experience than randomized clinical trials. Our purpose was to ob...

    Authors: Oliver Schwenn, Barbara Heckmann, Claudia Guzy and Paul J Miller

    Citation: BMC Ophthalmology 2010 10:21

    Content type: Research article

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  3. Despite growing number of intraocular lens power calculation formulas, there is no evidence that these formulas have good predictive accuracy in pediatric, whose eyes are still undergoing rapid growth and refr...

    Authors: Azlyn-Azwa Jasman, Bakiah Shaharuddin, Raja-Azmi M Noor, Shatriah Ismail, Zulkifli A Ghani and Zunaina Embong

    Citation: BMC Ophthalmology 2010 10:20

    Content type: Research article

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  4. Microvascular complications, including retinopathy and nephropathy are seen with type 1 diabetes. It is unknown whether functional changes in aqueous humor flow or intraocular pressure (IOP) develop in paralle...

    Authors: James T Lane, LuAnn Larson, Shan Fan, Julie A Stoner, Eyal Margalit and Carol B Toris

    Citation: BMC Ophthalmology 2010 10:19

    Content type: Research article

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  7. To describe and compare visual function measures of two groups of school age children (6-14 years of age) attending a specialist eyecare practice in Austria; one group referred to the practice from educational...

    Authors: Wolfgang Dusek, Barbara K Pierscionek and Julie F McClelland

    Citation: BMC Ophthalmology 2010 10:16

    Content type: Research article

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  8. The purpose of this study was to reduce the number of items, create a scoring method and assess the psychometric properties of the Freedom from Glasses Value Scale (FGVS), which measures benefits of freedom fr...

    Authors: Gilles Berdeaux, Juliette Meunier, Benoit Arnould and Muriel Viala-Danten

    Citation: BMC Ophthalmology 2010 10:15

    Content type: Research article

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  11. Although a leading cause of visual impairment and a treatable cause of blindness globally, the pattern of refractive errors in many populations is unknown. This study determined the pattern of refractive ocula...

    Authors: Abdulkabir A Ayanniyi, Francisca N Folorunso and Feyisayo G Adepoju

    Citation: BMC Ophthalmology 2010 10:12

    Content type: Research article

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  12. The mechanism by which vitrectomy improves macular edema in patients with branch retinal vein occlusion remains unclear, although intraocular levels of vascular endothelial growth factor have been suggested to...

    Authors: Hidetaka Noma, Hideharu Funatsu, Tatsuya Mimura, Shuichiro Eguchi and Katsunori Shimada

    Citation: BMC Ophthalmology 2010 10:11

    Content type: Research article

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  13. Given the growing number of ocular hypotensive medications available, it is important to be able to predict a positive response to therapy. The purpose of the present study was to identify predictors of an add...

    Authors: Eric Sellem, Jean François Rouland, Christophe Baudouin, Alain Bron, Philippe Denis, Jean-Philippe Nordmann and Jean Paul Renard

    Citation: BMC Ophthalmology 2010 10:10

    Content type: Research article

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  15. To assess the reliability of the measurements obtained with the PalmScan™, when compared with another standardized A-mode ultrasound device, and assess the consistency and correlation between the two methods.

    Authors: Raul Velez-Montoya, Eugene Mark Shusterman, Miriam Jessica López-Miranda, Mariana Mayorquin-Ruiz, Guillermo Salcedo-Villanueva, Hugo Quiroz-Mercado and Virgilio Morales-Cantón

    Citation: BMC Ophthalmology 2010 10:8

    Content type: Research article

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  16. Patients' understanding of their condition affect the choice of treatment. The aim of this study is to evaluate patients' understanding and treatment preferences before and after an information session on the ...

    Authors: Albert I Matti, Miriam C Keane, Helen McCarl, Pamela Klaer and Celia S Chen

    Citation: BMC Ophthalmology 2010 10:7

    Content type: Research article

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  18. Prior research has demonstrated that medication persistence (continued acquisition of therapy over time) is far from optimal among patients with glaucoma. The purpose of the present study was to evaluate persi...

    Authors: Gregory Reardon, Gail F Schwartz and Sameer Kotak

    Citation: BMC Ophthalmology 2010 10:5

    Content type: Research article

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  19. Prospective, multicenter, randomized, double-masked trials have shown latanoprost instilled once daily to be at least as effective as and generally superior to timolol administered twice daily and to be as eff...

    Authors: Philippe Denis, Christophe Baudouin, Alain Bron, Jean-Philippe Nordmann, Jean Paul Renard, Jean François Rouland, Eric Sellem and Mourad Amrane

    Citation: BMC Ophthalmology 2010 10:4

    Content type: Research article

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  20. Mutations in COL8A2 gene which encodes the collagen alpha-2 (VIII) chain have been identified in both familial and sporadic cases of Fuchs endothelial corneal dystrophy (FECD). Heterozygous mutations in the SLC4A...

    Authors: Boomiraj Hemadevi, Muthiah Srinivasan, Jambulingam Arunkumar, Namperumalsamy V Prajna and Periasamy Sundaresan

    Citation: BMC Ophthalmology 2010 10:3

    Content type: Research article

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  21. Studies have shown that early detection and treatment of neovascular age-related macular degeneration (NV-AMD) can delay vision loss and blindness. The objective of this study was to evaluate the efficacy/safe...

    Authors: Pamela A Weber, Barbara M Wirostko, Xiao Xu, Thomas F Goss and Gergana Zlateva

    Citation: BMC Ophthalmology 2010 10:2

    Content type: Research article

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  22. The objective of this study was to ascertain the scoring and assess the psychometric properties of the Eye-Drop Satisfaction Questionnaire (EDSQ), a 43-item Patient-Reported Outcome instrument developed to ass...

    Authors: Antoine Regnault, Muriel Viala-Danten, Hélène Gilet and Gilles Berdeaux

    Citation: BMC Ophthalmology 2010 10:1

    Content type: Research article

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  23. Previous research has suggested that the silicon BD Atomic Edge™ knife has superior performance characteristics when compared to a metal knife and performance similar to diamond knife when making various incis...

    Authors: John Albanese, Geoffrey Dugue, Valentin Parvu, Ann M Bajart and Edwin Lee

    Citation: BMC Ophthalmology 2009 9:15

    Content type: Research article

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  27. To report the prevalence of ear lobe crease (ELC), a sign of coronary heart disease, in subjects (more than 40 years old) with diabetes and find its association with diabetic retinopathy.

    Authors: Rajiv Raman, Padmaja Kumari Rani, Vaitheeswaran Kulothungan and Tarun Sharma

    Citation: BMC Ophthalmology 2009 9:11

    Content type: Research article

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  28. We describe a modified method for deepitheliazation prior to corneal cross linking (CXL). The technique may overcome the current corneal pachymetric limitation parameter (over 400 microns) that is necessary fo...

    Authors: George D Kymionis, Vasilios F Diakonis, Efekan Coskunseven, Mirco Jankov, Sonia H Yoo and Ioannis G Pallikaris

    Citation: BMC Ophthalmology 2009 9:10

    Content type: Technical advance

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  29. Although it has been suggested that alterations of nerve fiber layer vasculature may be involved in the etiology of eye diseases, including glaucoma, it has not been possible to examine this vasculature in-vivo. ...

    Authors: Drew Scoles, Daniel C Gray, Jennifer J Hunter, Robert Wolfe, Bernard P Gee, Ying Geng, Benjamin D Masella, Richard T Libby, Stephen Russell, David R Williams and William H Merigan

    Citation: BMC Ophthalmology 2009 9:9

    Content type: Technical advance

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  30. This paper reports population-based data on the prevalence and causes of visual impairment among children and adults in Botucatu, Brazil.

    Authors: Silvana Artioli Schellini, Shane R Durkin, Erika Hoyama, Flavio Hirai, Ricardo Cordeiro, Robert J Casson, Dinesh Selva and Carlos Roberto Padovani

    Citation: BMC Ophthalmology 2009 9:8

    Content type: Research article

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  32. With the increasing number of people participating in physical aerobic exercise, jogging in particular, we considered that it would be worth knowing if there are should be limits to the exercise with regard to...

    Authors: Konstantinos Natsis, Irene Asouhidou, George Nousios, Theodosios Chatzibalis, Konstantinos Vlasis and Vasilios Karabatakis

    Citation: BMC Ophthalmology 2009 9:6

    Content type: Research article

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  33. Benzalkonium chloride (BAC) is a common preservative used in ophthalmic solutions. The aim of this study was to compare the cytotoxic effects of BAC-containing ophthalmic solutions with a BAC-free ophthalmic s...

    Authors: Su Khoh-Reiter and Bart A Jessen

    Citation: BMC Ophthalmology 2009 9:5

    Content type: Research article

    Published on:

  35. Amblyopia and amblyogenic factors like strabismus and refractive errors are the most common vision disorders in children. Although different studies suggest that preschool vision screening is associated with a...

    Authors: Christine Schmucker, Robert Grosselfinger, Rob Riemsma, Gerd Antes, Stefan Lange, Wolf Lagrèze and Jos Kleijnen

    Citation: BMC Ophthalmology 2009 9:3

    Content type: Research article

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  36. Rhegmatogenous retinal detachment (RRD) is a potentially blinding condition and a common cause of ocular morbidity. Establishing an accurate estimate of disease incidence and distribution is an important first...

    Authors: Danny Mitry, David G Charteris, David Yorston, Brian W Fleck, Alan Wright, Harry Campbell and Jaswinder Singh

    Citation: BMC Ophthalmology 2009 9:2

    Content type: Study protocol

    Published on:

  38. To determine if novel measures of cardiovascular health are associated with prevalence or progression of age-related macular degeneration (AMD).

    Authors: Catherine A McCarty, Adam Dowrick, James Cameron, Barry McGrath, Luba D Robman, Peter Dimitrov, Gabriella Tikellis, Caroline Nicolas, John McNeil and Robyn Guymer

    Citation: BMC Ophthalmology 2008 8:25

    Content type: Research article

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  39. Strategies for prevention of eye injuries require knowledge of the cause of the injuries. This study was done to determine the patient characteristics, the cause of injury, and where cases of traumatic hyphaem...

    Authors: Adeyinka O Ashaye

    Citation: BMC Ophthalmology 2008 8:24

    Content type: Research article

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  40. The Early Treatment for Retinopathy of Prematurity study (ETROP), published in 2003, established new guidelines for treatment of retinopathy of prematurity (ROP) and demonstrated improved outcomes compared to ...

    Authors: Aaron M Alme, Michael L Mulhern, Thomas W Hejkal, Jane L Meza, Fang Qiu, David D Ingvoldstad and Eyal Margalit

    Citation: BMC Ophthalmology 2008 8:23

    Content type: Research article

    Published on:

  42. Glaucoma is a major cause of blindness worldwide and an increasingly significant global health problem. Glaucoma prevention and management efforts have been challenging due to inherent difficulty in developing...

    Authors: Suman S Thapa, Kurt H Kelley, Ger V Rens, Indira Paudyal and Lan Chang

    Citation: BMC Ophthalmology 2008 8:21

    Content type: Correspondence

    Published on:

  43. The aim of this study was to assess changes in metalloproteinases (MMP-2) and tissue inhibitor of metalloproteinases (TIMP-2) following selective laser trabeculoplasty (SLT) in patients with pseudoexfoliative ...

    Authors: Mauro Cellini, Pietro Leonetti, Ernesto Strobbe and Emilio C Campos

    Citation: BMC Ophthalmology 2008 8:20

    Content type: Research article

    Published on:

  44. To assess the occurrence and magnitude of refractive change in pseudophakic eyes undergoing 20 gauge pars plana vitrectomy without scleral buckling and to investigate possible aetiological factors.

    Authors: Sinead Byrne, James Ng, Anthony Hildreth, Jean-Pierre Danjoux and David HW Steel

    Citation: BMC Ophthalmology 2008 8:19

    Content type: Research article

    Published on:

  45. Branch retinal vein occlusion is a frequent cause of visual loss with currently insufficient treatment options. We evaluate the effect of Bevacizumab (Avastin®) treatment in patients with macular edema induced by...

    Authors: Mathias Abegg, Christoph Tappeiner, Ute Wolf-Schnurrbusch, Daniel Barthelmes, Sebastian Wolf and Johannes Fleischhauer

    Citation: BMC Ophthalmology 2008 8:18

    Content type: Research article

    Published on:

  46. Despite having the largest population in Africa, Nigeria has no accurate population based data to plan and evaluate eye care services. A national survey was undertaken to estimate the prevalence and determine ...

    Authors: Brendan Dineen, Clare E Gilbert, Mansur Rabiu, Fatima Kyari, Abdull M Mahdi, Tafida Abubakar, Christian C Ezelum, Entekume Gabriel, Elizabeth Elhassan, Adenike Abiose, Hannah Faal, Jonathan Y Jiya, Chinenyem P Ozemela, Pak Sang Lee and Murthy VS Gudlavalleti

    Citation: BMC Ophthalmology 2008 8:17

    Content type: Study protocol

    Published on:

  50. Stereoscopic assessment of the optic disc morphology is an important part of the care of patients with glaucoma. The aim of this study was to assess stereoviewing of stereoscopic optic disc images using an exa...

    Authors: Maged S Habib, James A Lowell, Nick S Holliman, Andrew Hunter, Daniella Vaideanu, Anthony Hildreth and David HW Steel

    Citation: BMC Ophthalmology 2008 8:13

    Content type: Research article

    Published on:

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BMC Ophthalmology

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