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  1. Mycotic keratitis is an important cause of corneal blindness world over including India. Geographical location and climate are known to influence the profile of fungal diseases. While there are several reports...

    Authors: Bibhudutta Rautaraya, Savitri Sharma, Sarita Kar, Sujata Das and Srikant K Sahu

    Citation: BMC Ophthalmology 2011 11:39

    Content type: Research article

    Published on:

  2. Retinitis pigmentosa is characterized by the sequential loss of rod and cone photoreceptors. The preservation of cones would prevent blindness due to their essential role in human vision. Rod-derived Cone Viab...

    Authors: Emmanuelle Clérin, Nicolas Wicker, Saddek Mohand-Saïd, Olivier Poch, José-Alain Sahel and Thierry Léveillard

    Citation: BMC Ophthalmology 2011 11:38

    Content type: Technical advance

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  3. Descemet's Stripping with Automated Endothelial Keratoplasty (DSAEK) is constantly gaining popularity in the management of endothelial dysfunctions such as bullous keratopathy or Fuchs' dystrophy.

    Authors: George D Kymionis, Dimitra M Portaliou, Takeshi Ide and Sonia H Yoo

    Citation: BMC Ophthalmology 2011 11:37

    Content type: Case report

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  4. Diabetic macular oedema is the leading causes of blindness. Laser photocoagulation reduces the risk of visual loss. However recurrences are common and despite laser treatment, patients with diabetic macular oe...

    Authors: Mustapha Norlaili, Shaharuddin Bakiah and Embong Zunaina

    Citation: BMC Ophthalmology 2011 11:36

    Content type: Research article

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  5. To identify the genetic defect associated with autosomal recessive congenital cataract (ARCC), mental retardation (MR) and ARCC, MR and microcephaly present in most patients in four Tunisian consanguineous fam...

    Authors: Manèl Chograni, Myriam Chaabouni, Faouzi Mâazoul, Hedi Bouzid, Abdelhafid Kraiem and Habiba B Bouhamed Chaabouni

    Citation: BMC Ophthalmology 2011 11:35

    Content type: Research article

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  6. Glial heterotopias are rare, benign, congenital, midline, non-teratomatous extracranial glial tissue. They may masquerade as encephalocoele or dermoid cyst and mostly present in nose. Herein, we present an unu...

    Authors: Ranju Sitaula, Gulshan B Shrestha, Nabin Paudel, Sneha Shrestha and Dev N Shah

    Citation: BMC Ophthalmology 2011 11:34

    Content type: Case report

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  7. Retinal detachment is a disorder of the eye in which sensory retina separates from the retinal pigment epithelium (RPE) due to accumulation of fluid in subretinal space. Pharmacological stimulation of fluid re...

    Authors: Pavel Iserovich, Qiong Qin and Konstantin Petrukhin

    Citation: BMC Ophthalmology 2011 11:33

    Content type: Research article

    Published on:

  8. The eMERGE (electronic MEdical Records and Genomics) network, funded by the National Human Genome Research Institute, is a national consortium formed to develop, disseminate, and apply approaches to research t...

    Authors: Carol J Waudby, Richard L Berg, James G Linneman, Luke V Rasmussen, Peggy L Peissig, Lin Chen and Catherine A McCarty

    Citation: BMC Ophthalmology 2011 11:32

    Content type: Research article

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  10. To report a case of disseminated fusariosis with endogenous endophthalmitis in a patient with acute lymphoblastic leukemia. Transfusion-associated immune modulation secondary to platelet transfusion could play...

    Authors: Tan Aik Kah, Ku Chui Yong and Ropilah Abdul Rahman

    Citation: BMC Ophthalmology 2011 11:30

    Content type: Case report

    Published on:

  11. The influence of serous retinal detachment (SRD) on retinal sensitivity in patients with branch retinal vein occlusion (BRVO) and macular edema remains unclear. This is despite the frequent co-existence of SRD...

    Authors: Hidetaka Noma, Hideharu Funatsu, Tatsuya Mimura and Katsunori Shimada

    Citation: BMC Ophthalmology 2011 11:29

    Content type: Research article

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  12. Tourette syndrome is a neurologic disorder that is characterized by repetitive muscle contractions that produce stereotyped movements or sounds. Approximately 50% of individuals with TS also exhibit obsessive-...

    Authors: Artemios Kandarakis, Michael Karampelas, Vasileios Soumplis, Christos Panos, Nikolaos Makris, Stylianos Kandarakis and Dimitrios Karagiannis

    Citation: BMC Ophthalmology 2011 11:28

    Content type: Case report

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  13. To report a case with hypotony due to late leakage of the filtering bleb performed during childhood and treated surgically using human pericardium graft.

    Authors: Dimitris Papaconstantinou, Ilias Georgalas, Sergios Taliantzis, Chrysanthi Koutsandrea, Ioannis Ladas and Gerassimos Georgopoulos

    Citation: BMC Ophthalmology 2011 11:27

    Content type: Case report

    Published on:

  14. Reliable data are a pre-requisite for planning eye care services. Though conventional cross sectional studies provide reliable information, they are resource intensive. A novel rapid assessment method was used...

    Authors: Srinivas Marmamula, Sreenivas R Madala and Gullapalli N Rao

    Citation: BMC Ophthalmology 2011 11:26

    Content type: Research article

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  15. Visual impairment caused by cataracts not only affects an individual's quality of life but can also have a profound impact on other important psychological factors and on the economic circumstances of individu...

    Authors: Beverley M Essue, Maree L Hackett, Andreas Mueller, Nguyen Thi Hanh Duc, Huynh Tan Phuc and Stephen Jan

    Citation: BMC Ophthalmology 2011 11:25

    Content type: Study protocol

    Published on:

  17. A noninferiority trial was conducted to evaluate the efficacy of a single evening dose of fixed-combination latanoprost 50 μg/mL and timolol 0.5 mg/mL (Xalacom®; LTFC), in Chinese patients with primary open-angle...

    Authors: Jia-Liang Zhao, Jian Ge, Xiao-Xin Li, Yu-Min Li, Yao-Hua Sheng, Nai-Xue Sun, Xing-Huai Sun, Ke Yao and Zheng Zhong

    Citation: BMC Ophthalmology 2011 11:23

    Content type: Research article

    Published on:

  18. Alzheimer's disease (AD) and age-related macular degeneration (AMD) share several pathological hallmarks including β-amyloid (Aβ) accumulation, oxidative stress, and apoptotic cell death. The causes of AD and ...

    Authors: Bhanu Dasari, Jaya RP Prasanthi, Gurdeep Marwarha, Brij B Singh and Othman Ghribi

    Citation: BMC Ophthalmology 2011 11:22

    Content type: Research article

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  19. The present study investigates two different treatment options for convergence insufficiency CI for a group of children with reading difficulties referred by educational institutes to a specialist eye clinic i...

    Authors: Wolfgang A Dusek, Barbara K Pierscionek and Julie F McClelland

    Citation: BMC Ophthalmology 2011 11:21

    Content type: Research article

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  20. The performance of glaucoma diagnostic systems could be conceivably improved by the integration of functional and structural test measurements that provide relevant and complementary information for reaching a...

    Authors: Dimitrios Bizios, Anders Heijl and Boel Bengtsson

    Citation: BMC Ophthalmology 2011 11:20

    Content type: Research article

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  22. Pseudoexfoliation (PXF) is a recognized risk factor for developing cataract, glaucoma and lens dislocation. PXF is also associated with increased risk of complications during cataract surgery due to poor mydri...

    Authors: Tarek A Shazly, Abdelsattar N Farrag, Asmaa Kamel and Ashraf K Al-Hussaini

    Citation: BMC Ophthalmology 2011 11:18

    Content type: Research article

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  26. To investigate the clinical relevance of two different preservative formulations, we compared 1-year incidence rates of additional coding of dry eye, ocular infection, or ocular surface disease (either dry eye...

    Authors: Gail F Schwartz, Sameer Kotak, Jack Mardekian and Joel M Fain

    Citation: BMC Ophthalmology 2011 11:14

    Content type: Research article

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  27. Because latanoprost and the original formulation of travoprost that included benzalkonium chloride (BAK) have been shown to be similar with regard to tolerability, we compared initial topical intraocular press...

    Authors: Joel M Fain, Sameer Kotak, Jack Mardekian, Jason Bacharach, Deepak P Edward, Steven Rauchman, Teresa Brevetti, Janet L Fox and Cherie Lovelace

    Citation: BMC Ophthalmology 2011 11:13

    Content type: Research article

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  31. Ophthalmic viscosurgical devices (OVDs) are widely used in phacoemulsification cataract surgery to maintain adequate intraocular space, stabilize ocular tissue during the operation and decrease the possible da...

    Authors: Marilita M Moschos, Irini P Chatziralli and Theodoros N Sergentanis

    Citation: BMC Ophthalmology 2011 11:9

    Content type: Research article

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  32. Although in vitro and in vivo laboratory studies have suggested that benzalkonium chloride (BAK) in topical ophthalmic solutions may be detrimental to corneal epithelial cells, multiple short- and long-term cl...

    Authors: Gerard Ryan Jr, Joel M Fain, Cherie Lovelace and Karl M Gelotte

    Citation: BMC Ophthalmology 2011 11:8

    Content type: Research article

    Published on:

  33. To describe the methodology of the Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetic Study III, an ongoing epidemiological study to estimate the prevalence of Diabetes and Diabetic Ret...

    Authors: Swakshyar Saumya Pal, Rajiv Raman, Suganeswari Ganesan, Chinmaya Sahu and Tarun Sharma

    Citation: BMC Ophthalmology 2011 11:7

    Content type: Study protocol

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  35. Scotopic function is an important marker of many retinal diseases and is increasingly used as an outcome measure in clinical trials, such as those investigating gene therapy for Lebers congenital amaurosis. Sc...

    Authors: Michael D Crossland, Vy A Luong, Gary S Rubin and Fred W Fitzke

    Citation: BMC Ophthalmology 2011 11:5

    Content type: Technical advance

    Published on:

  36. Pituitary adenoma may present with neuro-ophthalmic manifestations and, typically, rapid tumor expansion is the result of apoplexy. Herein, we present the first case of an isolated sixth cranial nerve palsy as...

    Authors: Norman Saffra, Elizabeth Kaplow, Irina Mikolaenko, Alice Kim, Benjamin Rubin and Jafar Jafar

    Citation: BMC Ophthalmology 2011 11:4

    Content type: Case report

    Published on:

  37. The observation of cytokeratins (CK's) in mass spectrometry based studies raises the question of whether the identified CK is a true endogenous protein from the sample or simply represents a contaminant. This ...

    Authors: Mikkel Lyngholm, Henrik Vorum, Kim Nielsen, Niels Ehlers and Bent Honoré

    Citation: BMC Ophthalmology 2011 11:3

    Content type: Research article

    Published on:

  38. Cataract and glaucoma are the major causes of blindness in Nepal. Bhaktapur is one of the three districts of Kathmandu valley which represents a metropolitan city with a predominantly agrarian rural periphery....

    Authors: Suman S Thapa, Rosa VD Berg, Shankar Khanal, Indira Paudyal, Pooja Pandey, Nhukesh Maharjan, Shankha N Twyana, Govinda Paudyal, Reeta Gurung, Sanduk Ruit and Ger HMBV Rens

    Citation: BMC Ophthalmology 2011 11:2

    Content type: Research article

    Published on:

  39. Excessive wound healing, with scarring of the episcleral tissue or encapsulation of the filtering bleb is the main reason for failure in trabeculectomy. Ranibizumab, an inhibitor of the Vascular Endothelial Gr...

    Authors: Frank Bochmann, Claude Kaufmann, Christoph N Becht, Ivo Guber, Michael Kaiser, Lucas M Bachmann and Michael A Thiel

    Citation: BMC Ophthalmology 2011 11:1

    Content type: Study protocol

    Published on:

  40. Age-related macular degeneration (AMD) is the leading cause of blindness in Western countries. Numerous risk factors have been reported but the evidence and strength of association is variable. We aimed to ide...

    Authors: Usha Chakravarthy, Tien Y Wong, Astrid Fletcher, Elisabeth Piault, Christopher Evans, Gergana Zlateva, Ronald Buggage, Andreas Pleil and Paul Mitchell

    Citation: BMC Ophthalmology 2010 10:31

    Content type: Research article

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  44. Gap junction channels allow direct metabolically and electrical coupling between adjacent cells in various mammalian tissues. Each channel is composed of 12 protein subunits, termed connexins (Cx). In the mous...

    Authors: Goran Söhl, Antonia Joussen, Norbert Kociok and Klaus Willecke

    Citation: BMC Ophthalmology 2010 10:27

    Content type: Research article

    Published on:

  45. A European-wide population based case-control study (European rare cancer study) undertaken in nine European countries examined risk factors for uveal melanoma. They found a positive association between cooks ...

    Authors: Andrea Schmidt-Pokrzywniak, Karl-Heinz Jöckel, Anja Marr, Norbert Bornfeld and Andreas Stang

    Citation: BMC Ophthalmology 2010 10:26

    Content type: Research article

    Published on:

  46. Gene silencing in the retina using RNA interference could open broad possibilities for functional studies of genes in vivo and for therapeutic interventions in eye disorders. Therefore, there is a considerable de...

    Authors: Andrey Turchinovich, Georg Zoidl and Rolf Dermietzel

    Citation: BMC Ophthalmology 2010 10:25

    Content type: Technical advance

    Published on:

  47. To use a new medium to dynamically visualize serial optical coherence tomography (OCT) scans in order to illustrate and elucidate the pathogenesis of idiopathic macular hole formation, progression, and surgica...

    Authors: Ronald C Gentile, Gennady Landa, Mauricio E Pons, Dean Eliott and Richard B Rosen

    Citation: BMC Ophthalmology 2010 10:24

    Content type: Case report

    Published on:

  48. To describe, a yet non-documented complication of GDI surgery (glaucoma drainage incision surgery) - anterior to posterior segment migration of Ahmed Glaucoma Valve (AGV) tube.

    Authors: Vishnu S Gupta, Harinder S Sethi, Malvika Gupta, Anuj Mehta, Shivram Singh, Pankaj Yadav and KPS Malik

    Citation: BMC Ophthalmology 2010 10:23

    Content type: Case report

    Published on:

  49. Alzheimer's disease (AD) and age-related macular degeneration (AMD) share several pathological features including β-amyloid (Aβ) peptide accumulation, oxidative damage, and cell death. The causes of AD and AMD...

    Authors: Bhanu Dasari, Jaya RP Prasanthi, Gurdeep Marwarha, Brij B Singh and Othman Ghribi

    Citation: BMC Ophthalmology 2010 10:22

    Content type: Research article

    Published on:

  50. Prospective, observational studies that enroll large numbers of patients with few exclusion criteria may better reflect actual ongoing clinical experience than randomized clinical trials. Our purpose was to ob...

    Authors: Oliver Schwenn, Barbara Heckmann, Claudia Guzy and Paul J Miller

    Citation: BMC Ophthalmology 2010 10:21

    Content type: Research article

    Published on:

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