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Table 1 Case review of surgical treatment and postoperative outcome of RP with FTMH

From: Flap technique-assisted surgeries for advanced retinitis pigmentosa complicated with macular hole: a case report and literature review

Author Year Origin of population Subject number Number of eyes Associated disease Surgical method BCVA change OCT change
Vingolo et al. [19] 2015 Italy 3 3   PPV, ILM peeling, gas tamponade 3 improved 3 complete FTMH closure
Jin et al. [20] 2008 Japan 4 4 PVD, high myopia, RD, CME PPV, ILM peeling, C3F8 injection 3 improved, 1 improved partially 4 complete FTMH closure
Panagiotou et al. [2] 2020 Greece 1 1 PVD, absence of EZ PPV, ILM peeling, C2F6 injection 1 unchanged 1 complete FTMH closure
Hagiwara et al. [5] 2011 Japan 2 2 RPE atrophy PPV, ILM peeling, SF6 injection 1 improved, 1 worsened 2 complete FTMH closure
Liu et al. [21] 2020 China 2 2 LHEP, RD, foveal detachment 1. PPV, ILM peeling, LHEP transplantation, autologous blood, C3F8 injection2. PPV, ILM peeling, laser, LHEP transplantation, C3F8 injection 2 improved 2 complete FTMH closure
Yan et al. [14] 2018 China 4 4   PPV, ILM peeling, SF6 or C3F8 or silicon injection 2 improved, 1 unchanged, 1 worsened 3 complete FTMH closure,1 remained unclosed
Ratra et al. [22] 2013 India 5 5 CME PPV, ILM peeling, C3F8 or silicon injection 2 improved, 1 unchanged, 2 worsened 3 complete FTMH closure,2 remained unclosed
Enani et al. [23] 2017 Saudi Arabia 1 1   PPV, ILM peeling, gas tamponade 1 unchanged 1 complete FTMH closure
García-Fernández et al. [24] 2013 Spain 1 1 SRF, PVD PPV, ILM peeling, SF6 injection 1 unchanged 1 reopened 2 years later
Amemiya et al. [25] 2002 Japan 1 1   PPV, ILM peeling, gas tamponade 1 improved 1 complete FTMH closure
  1. PPV pars plana vitrectomy; ILM internal limiting membrane; FTMH full-thickness macular hole; PVD posterior vitreous detachment; RD retinal detachment; CME cystoid macular edema; EZ ellipsoid zone; RPE retinal pigment epithelium; LHEP lamellar-hole associated epiretinal proliferation