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Table 1 Patient characteristics

From: Long-term effects of intravitreal bevacizumab and aflibercept on intraocular pressure in wet age-related macular degeneration

  Non-switched patients, n = 71 Switched patients, n = 49  
Bevacizumab Bevacizumaba Aflibercepta p-value
Sex (males), n (%) 29 (41) 15 (31) 15 (31) 0.39
Age at first injection (years), mean ± SD 78.3 ± 7.6 76.7 ± 8.0 78.0 ± 7.9 0.51
Glaucoma, n (%)
 Treated eye 3 (4) 5 (10) 5 (10) 0.36
 Fellow eye 4 (6) 5 (10) 5 (10) 0.57
Pseudophakia, n (%)
 Treated eye 33 (46) 15 (31) 23 (47) 0.16
 Fellow eye 31 (44) 17 (35) 21 (43) 0.58
Baseline IOP (mmHg), median (Q1; Q3)
 Treated eye 13 (12; 16) 13 (10; 15) 13 (11; 15) 0.85
 Fellow eye 14 (11; 16) 12 (11; 16) 14 (10; 17) 0.82
Last IOP (mmHg), median (Q1; Q3)
 Treated eye 13 (11; 15) 13 (11; 15) 12 (10; 14) 0.069
 Fellow eye 12 (10; 15) 14 (10; 17) 13 (10; 15) 0.26
Follow-up (days), mean ± SD 495.8 ± 245.2 494.5 ± 351.4 700.2 ± 331.0 < 0.001
No. of injections, median (Q1; Q3) 10 (9; 14.5) 9 (6; 15) 15 (12; 21) < 0.001
Injection interval (days), median (Q1; Q3) 41.7 (34.2; 49.0) 36.5 (34.0; 40.3) 35.1 (30.4; 55.5) 0.008
  1. aSame individuals